Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes

This publication has 22 references indexed in Scilit:

• Effects of low doses of N-nitrosomorpholine on the development of early stages of hepatocarcinogenesis
  Carcinogenesis: Integrative Cancer Research, 1995
• The potential for the use of cell proliferation and oncogene expression as intermediate markers during liver carcinogenesis
  Cancer Letters, 1995
• The quantitation of altered hepatic foci during multistage hepatocarcinogenesis in the rat: Transforming growth factor α expression as a marker for the stage of progression
  Cancer Letters, 1995
• Metastasizing tumors in rats treated with alkylating carcinogens
  Carcinogenesis: Integrative Cancer Research, 1995
• p53 mutations in early neoplastic lesions of the urinary bladder in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine
  Carcinogenesis: Integrative Cancer Research, 1994
• Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by continuous oral exposure to N-nitrosomorpholine
  Carcinogenesis: Integrative Cancer Research, 1994
• Establishment of Multi-Organ Carcinogenesis Bioassay Using Rats Treated With A Combination of Five Different Carcinogens.
  Journal of Toxicologic Pathology, 1992
• 3.1 Cytochemical, microbiochemical and molecular genetic analysis of chemical carcinogenesis
  Progress in Histochemistry and Cytochemistry, 1991
• Overexpression of P-glycoprotein rat hepatocellular carcinomas induced with N-nitrosomorpholine
  Carcinogenesis: Integrative Cancer Research, 1990
• Hepatocarcinogens induce decrease in mRNA transcripts of receptors for insulin and epidermal growth factor in the rat liver
  Biochemical and Biophysical Research Communications, 1987