Alicyclic β-amino acids in Medicinal Chemistry
- 30 June 2005
- journal article
- review article
- Published by Springer Nature in Amino Acids
- Vol. 29 (2) , 89-100
- https://doi.org/10.1007/s00726-005-0212-y
Abstract
The structural element of alicyclic β-amino acids shows some remarkable biological effects: For some 5- and 6-membered β-amino acids a unique anti fungal activity has been observed, 7-membered β-amino acid derivatives have been investigated for neurological disorders. The application of 5-, 6- and 7-membered alicyclic β-amino acids in Medicinal Chemistry will be reported. Caption of figureKeywords
This publication has 41 references indexed in Scilit:
- Enantioselective Hydrogenation of Tetrasubstituted Olefins of Cyclic β-(Acylamino)acrylatesJournal of the American Chemical Society, 2003
- Efficient Asymmetric Synthesis of β-Amino Acid BAY 10-8888/PLD-118, a Novel Antifungal for the Treatment of Yeast InfectionsSynthesis, 2002
- Efficient Asymmetric Synthesis of Unnatural β-Amino AcidsSynthesis, 2001
- Dopamine transporter imaging as an in vivo marker of dopaminergic neuronsDrugs of the Future, 2001
- New investigational antifungal agents for treating invasive fungal infectionsExpert Opinion on Investigational Drugs, 2000
- Pharmacotherapies for Treatment of Cocaine Abuse: Preclinical AspectsJournal of Medicinal Chemistry, 1999
- Synthesis of Racemic and Optically Active Cispentacin (FR109615) Using Intramolecular Nitrone-Olefin Cycloaddition.CHEMICAL & PHARMACEUTICAL BULLETIN, 1993
- An Expeditious Asymmetric Synthesis of (-)-(1R,2S) -CispentacinSynlett, 1993
- Synthesis and cocaine receptor affinities of 3-phenyl-2-(3′-methyl-1,2,4-oxadiazole-5′-yl)tropane isomersJournal of the Chemical Society, Chemical Communications, 1993
- The dopamine hypothesis of the reinforcing properties of cocaineTrends in Neurosciences, 1991