Fermentable sugar in fasting urine
- 1 January 1933
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 27 (5) , 1598-1608
- https://doi.org/10.1042/bj0271598
Abstract
Ammonium salts, in physiological amounts, lower the total sugar and non-fermentable "sugar" found in urine, when the determinations are made by the sensitive Shaffer-Hart-mann reagents. The fermentable sugar value may be unaltered. The use of KH2PO4 followed by MgO constitutes a method of clearing normal urine. The filtrates are suitable for "sugar" determinations. KH2PO4-MgO can be used in conjunction with H2SO4-Lloyd''s reagent for clearing urines previous to "sugar" determinations. The values for fermentable sugar in normal fasting urine may vary with the clearing agent and with the Cu reagent. All the variations of method permit the recovery of glucose added to urine, in the form of extra fermentable sugar. The amount of fermentable sugar in normal fasting urine can be varied by the state of dilution previous to the application of H2SO4-Lloyd''s reagent. Provided the method of clearing and the oxidizing reagent correctly estimate small amounts of added glucose, the lower values for fermentable sugar should be accepted as more nearly correct. Using the methods which give the higher results for fermentable sugar in urine the oral ingestion of glucose results in slight but distinct increases in this fraction. These increases can not be correlated with the increase in the blood sugar. When the usual renal threshold for sugar is passed, large amounts of sugar appear in the urine. It is concluded that some substance removable by yeast other than glucose exists in normal human fasting urine.This publication has 5 references indexed in Scilit:
- The sugars of urineBiochemical Journal, 1932
- The sugars of urineBiochemical Journal, 1932
- The sugars of urineBiochemical Journal, 1932
- Fermentable sugar in normal urineBiochemical Journal, 1931
- The non-sugar reducing substances of human blood, with special reference to glutathioneBiochemical Journal, 1930