• 1 January 1977
    • journal article
    • research article
    • Vol. 38  (2) , 251-253
Abstract
At 35 days old, chickens inoculated at 1 day old with the infectious bursal disease virus (IBDV) had significantly lower antibody titers against M. synoviae, Newcastle disease virus and infectious bronchitis virus than did those never inoculated with IBDV. The IBDV also had a marked effect on the development of air-sac lesions. Birds infected with IBDV that were later inoculated with M. synoviae (day 14), Newcastle disease virus (days 14 and 28) and infectious bronchitis virus (days 14 and 28) experienced an increased incidence and greater severity of airsacculitis than did chicks which were not exposed to IBDV. [The IBDV infection decreased the immune responsiveness of the chicks to Mycoplasma.].