THE DEVELOPMENT OF A CERVICAL SMEAR PREPARATION PROCEDURE FOR THE BIOPEPR IMAGE-ANALYSIS SYSTEM
- 1 January 1981
- journal article
- research article
- Vol. 3 (1) , 73-80
Abstract
The preparation procedure for the BioPEPR automated image analysis system is described. Cervical cells are collected in a preservative solution and disaggregated by an automated syringing apparatus, giving about 50% single cells. After centrifugation, the preservative solution is discarded, 2% polyetheleneglycol in 50% ethanol (carbowax) is added, and the cell solution is automatically spread onto a glass slide, resulting in a cell density of about 50 cells/mm2 in the central area of the smear. Increasing cell density leads to a gradual linear decrease in single cells. All preparation steps were critically evaluated, and the possibility of implementing this preparation procedure in a fully automated system is discussed. [Implications for cancer diagnosis were discussed.].This publication has 5 references indexed in Scilit:
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