GUILLAIN-BARRÉ SYNDROME ASSOCIATED WITH PORPHYRINURIA

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Abstract
A case of Guillain-Barre syndrome is presented in a patient who demonstrated the urinary excretion of porphobilinogen, uroporphyrin and coproporphyrin. In view of this patient demonstrating an albuminocytologic dissociation of the spinal fluid, papilledema, increased cerebrospinal fluid pressure, as well as the type of neuritis; it is felt that the primary diagnosis is Guillain-Barre syndrome with porphyrinuria representing either a secondary change or a fortuitous finding. A distinction is made between "secondary porphyria," which applies to increased excretion of coproporphyrin, and the porphyrinuria observed in this case, which, in addition to increased urinary excretion of coproporphyrin, also demonstrated porphobilinogen and coproporphyrin.