Turbidimetric Bioassay for Carbenicillin
Open Access
- 1 March 1973
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 3 (3) , 364-368
- https://doi.org/10.1128/aac.3.3.364
Abstract
A quantitative turbidimetric bioassay has been developed for carbenicillin with the use of a strain of Escherichia coli . The assay is relatively specific for carbenicillin and is not affected by 10% (wt/wt) benzylpenicillin. It has been demonstrated to be more precise than the plate diffusion assay. Since it is readily automated, it is also faster and less expensive. The influence of pH, time, and extent of growth on the assay has been evaluated.Keywords
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