Implications of the Neglect of Stereochemistry in Pharmacokinetics and Clinical Pharmacology
Open Access
- 1 October 1987
- journal article
- case report
- Published by SAGE Publications in Drug Intelligence & Clinical Pharmacy
- Vol. 21 (10) , 827-829
- https://doi.org/10.1177/106002808702101013
Abstract
An outline is given of the implications of stereoselectivity in biological action and the use of racemic fixed-ratio combinations in pharmacology and pharmacotherapeutics. Pitfalls of the neglect of stereochemistry, such as generation of senseless pharmacokinetic data, are exemplified and emphasized.Keywords
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