Safety and Efficacy of Cefixime versus Cefaclor in Respiratory Tract Infections
- 1 August 1989
- journal article
- research article
- Published by Taylor & Francis in Journal of Chemotherapy
- Vol. 1 (4) , 257-260
- https://doi.org/10.1080/1120009x.1989.11738903
Abstract
A randomized controlled study design was used to compare the efficacy of cefixime versus cefaclor in 30 patients suffering from lower respiratory tract infections. Patients were treated with a 10 to 11 day course of cefixime 200 mg b.i.d. or cefaclor 500 mg t.i.d. The overall clinical response (cured and improved) in the 3 evaluable patients of the cefixime group was 100%. 12 of the 14 patients of the cefaclor group were cured or improved. In the two other patients the symptoms remained unchanged. The bacteriological efficacy in both groups was comparable. Adverse effects were not reported during the study.This publication has 2 references indexed in Scilit:
- Comparative bactericidal activity of cefixime, carumonam, enoxacin and roxithromycin with those of other antibiotics against resistant Haemophilus influenzae including β-lactam tolerant strainsJournal of Antimicrobial Chemotherapy, 1987
- Comparative in vitro activity and beta-lactamase stability of FR 17027, a new orally active cephalosporinAntimicrobial Agents and Chemotherapy, 1984