Identification of Serum-Responsive Elements in the Promoter of Human Calcyclin, a Growth-Regulated Gene
- 1 April 1989
- journal article
- research article
- Published by Mary Ann Liebert Inc in DNA
- Vol. 8 (3) , 171-177
- https://doi.org/10.1089/dna.1.1989.8.171
Abstract
The calcyclin gene is growth regulated in a number of cell types from different animal species. We have identified in the promoter region of the human calcyclin gene the sequences responsible for its growth regulation by serum. A number of deletion mutants and synthetic nucleotides, all driving the chloramphenicol transferase (CAT) gene, were constructed for this purpose. Serum-responsive elements can be localized in the last 42 bp immediately upstream from the CAP site.This publication has 27 references indexed in Scilit:
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