Differentiated parental DNA strands confer developmental asymmetry on daughter cells in fission yeast
- 1 April 1987
- journal article
- Published by Springer Nature in Nature
- Vol. 326 (6112) , 466-470
- https://doi.org/10.1038/326466a0
Abstract
The two strands of the DNA molecule are complementary but not identical. Hence, upon semiconservative replication, different parental DNA strands are segregated to daughter cells. A molecular analysis suggests that the process of fission yeast mating-type interconversion uses asymmetry of the DNA strands to generate a regular lineage of cellular differentiation.Keywords
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