Albumin Excretion as a Measure of Glomerular Dysfunction in Children
Open Access
- 1 August 1970
- journal article
- review article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 45 (242) , 496-501
- https://doi.org/10.1136/adc.45.242.496
Abstract
The urine albumin/creatinine concentration ratio (UA/UC) and the albumin excretion rate per unit weight (UAV/Wt) have been compared with the theoretically ideal parameter for measuring glomerular damage, clearance of albumin/clearance of creatinine (CA/CC), using a simple sensitive immunochemical technique for albumin. It is shown that UA/UC on random urine specimens can be as satisfactorily used to predict CA/CC as UAV/Wt. Normal data over a wide range of body size of this simple parameter are presented; higher values in the newborn reflect increased permeability of the neonatal glomerulus.Keywords
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