Erythroid transcription factor NF-E2 is a haematopoietic-specific basic–leucine zipper protein
- 1 April 1993
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 362 (6422) , 722-728
- https://doi.org/10.1038/362722a0
Abstract
Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2.This publication has 54 references indexed in Scilit:
- Importance of globin gene order for correct developmental expression.Genes & Development, 1991
- Globin gene regulation and switching: Circa 1990Cell, 1990
- A major positive regulatory region located far upstream of the human alpha-globin gene locus.Genes & Development, 1990
- Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene clusterBlood, 1990
- Human gamma- to beta-globin gene switching in transgenic mice.Genes & Development, 1990
- Developmental regulation of human fetal-to-adult globin gene switching in transgenic miceNature, 1990
- Developmental regulation of β-globin gene switchingCell, 1988
- Position-independent, high-level expression of the human β-globin gene in transgenic miceCell, 1987
- The "beta-like-globin" gene domain in human erythroid cells.Proceedings of the National Academy of Sciences, 1985
- γ-β-Thalassaemia studies showing that deletion of the γ- and δ-genes influences β-globin gene expression in manNature, 1980