Optimized heteronuclear cross polarization in liquids

Abstract
It is demonstrated by theory, simulation, and experiment that it is possible to optimize heteronuclear cross-polarization experiments in liquids to such an extent that it becomes possible to transfer polarization uniformly through heteronuclear one-bond and long-range couplings. It is found that cross polarization is competitive with pulsed transfers, such as INEPT or DEPT, for the preparation of directly detected low-γ nuclei. However for proton detection after two-way transfer, experiments employing heteronuclear multiple quantum coherence are usually more sensitive than cross-polarization experiments.

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