THE HORMONAL INDUCTION OF MATING RESPONSES IN THE SPAYED-ADRENALECTOMIZED FEMALE RAT

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Abstract
Adrenalectomy lowers the sensitivity of spayed [female] rats to estrogen and to progesterone as demonstrated by tests for sexual receptivity following injns. of estradiol benzoate alone and followed by progesterone. There is some evidence to support a hypothesis that sexual receptivity can be induced in the spayed rat by estrogen alone only in the presence of adrenal cortical tissue as a source of progesterone activity.