Mathematical model for studying genetic variation in terms of restriction endonucleases.
- 1 October 1979
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (10) , 5269-5273
- https://doi.org/10.1073/pnas.76.10.5269
Abstract
A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this model are presented for estimating the number of nucleotide substitutions between two populations or species. To express the degree of polymorphism in a population at the nucleotide level, a measure called "nucleotide diversity" is proposed.This publication has 12 references indexed in Scilit:
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