Immunoprecipitation of [ 3 H]Dihydroartemisinin Translationally Controlled Tumor Protein (TCTP) Adducts from Plasmodium falciparum -Infected Erythrocytes by Using Anti-TCTP Antibodies
Open Access
- 1 August 2001
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 45 (8) , 2397-2399
- https://doi.org/10.1128/aac.45.8.2397-2399.2001
Abstract
Artemisinin and its derivatives are endoperoxide-containing antimalarial drugs that appear to form adducts in situ with thePlasmodium falciparum translationally controlled tumor protein (TCTP) homolog. Immunoprecipitation with antibody to recombinant TCTP suggests that adducts may form with both monomeric and dimeric TCTP.Keywords
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