ASYMMETRIC HYDROGENATIONS OF N-PYRUVOYL-(S)-AMINO ACID ESTERS BY USING SODIUM BOROHYDRIDE. A SOLVENT EFFECT
- 5 August 1983
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 12 (8) , 1225-1228
- https://doi.org/10.1246/cl.1983.1225
Abstract
N-Pyruvoyl-(S)-amino acid isobutyl esters were hydrogenated with sodium borohydride(NBH) in several alcoholic solvents, and N-[(R)-lactoyl]-(S)-amino acid esters were obtained with diastereoisomeric purity of up to 44%. Significant solvent effect on the diastereoisomeric purity of the product was observed.This publication has 8 references indexed in Scilit:
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