Molecular clocks: four decades of evolution
- 1 August 2005
- journal article
- review article
- Published by Springer Nature in Nature Reviews Genetics
- Vol. 6 (8) , 654-662
- https://doi.org/10.1038/nrg1659
Abstract
During the past four decades, the molecular-clock hypothesis has provided an invaluable tool for building evolutionary timescales, and has served as a null model for testing evolutionary and mutation rates in different species. Molecular clocks have also influenced the development of theories of molecular evolution. As DNA-sequencing technologies have progressed, the use of molecular clocks has increased, with a profound effect on our understanding of the temporal diversification of species and genomes.Keywords
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