Protein kinase C translocation in relation to proliferative state of C3H 10T1/2 cells
- 6 October 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 206 (2) , 283-286
- https://doi.org/10.1016/0014-5793(86)80997-8
Abstract
Protein kinase C (PKC) activity of cytosol and membrane fractions of 10T cells was studied. In cytosol of fast growing cells PKC activity was found in material eluted with 0.150 M NaCl whereas in membrane fractions activity was eluted with 0.065 and 0.150 M NaCl. In the membrane fraction of confluent cells, in contrast to cytosol, very low PKC activity was observed. The translocation pattern of PKC activity eluted with 0.065 M NaCl may be associated with proliferation.
Keywords
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