A NEW ENANTIOSELECTIVE ASYMMETRIC SYNTHESIS OF TRI-CO-ORDINATE PHOSPHORUS COMPOUNDS FROM DI-CO-ORDINATE λ3-ARYL(ALKYL)IMINOPHOSPHINES
- 1 April 1988
- journal article
- research article
- Published by Taylor & Francis in Phosphorus and Sulfur and the Related Elements
- Vol. 36 (3-4) , 267-270
- https://doi.org/10.1080/03086648808079022
Abstract
The reaction of di-co-ordinate λ3-aryl(alkyl)iminophosphines (1) with achiral alcohols in the presence of optically active tertiary amines has been found to proceed in an asymmetric way affording optically active O-alkyl amidophosphonites (2). N-(2,4,6-Tris-t-butylphenyl)amido-O-methyl-phenyl-phosphonite (2a) was obtained in this way with 55% ee and the absolute configuration (S) was chemically linked with (+)-(R)-O-methyl t-butanephosphonothioic acid.Keywords
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