Fine Mapping of Milk Production QTL on BTA6 by Combined Linkage and Linkage Disequilibrium Analysis
- 1 April 2004
- journal article
- Published by American Dairy Science Association in Journal of Dairy Science
- Vol. 87 (3) , 690-698
- https://doi.org/10.3168/jds.s0022-0302(04)73212-9
Abstract
Combined linkage and linkage disequilibrium analysis were used to refine the position of a previously detected QTL affecting milk production traits on bovine chromosome 6. Through a series of single- and multitrait and single- and multipoint QTL analyses, the QTL could be positioned to a 7.5-cM interval surrounded by the markers BMS2508 and FBN12. The most significant results were found for fat percentage and protein percentage. This effect seemed to be caused by a QTL allele embedded in one specific marker haplotype that caused a reduction in fat and protein yields and a concomitant increase of milk yield, thus resulting in a marked reduction of fat and protein percentages.Keywords
Funding Information
- Council of Norway
- Geno Breeding
- A. I. Association
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