Hippocampal sclerosis is a progressive disorder: A longitudinal volumetric MRI study
- 24 February 2003
- journal article
- research article
- Published by Wiley in Annals of Neurology
- Vol. 53 (3) , 413-416
- https://doi.org/10.1002/ana.10509
Abstract
Twelve patients with refractory temporal lobe epilepsy and unilateral hippocampal sclerosis had repeat volumetric magnetic resonance imaging scans after a mean of 3.4 years to determine whether progressive hippocampal volume loss occurred. Seizure-free patients showed no change in hippocampal volume. Patients with continuing seizures had a decline in ipsilateral hippocampal volume that correlated with seizure frequency. Patients with medically refractory temporal lobe epilepsy and unilateral hippocampal sclerosis have progressive hippocampal atrophy. Ann Neurol 2003;53:413–416Keywords
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