The familial nature of multiple sclerosis

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Abstract
Increasingly, MS patients ask neurologists about the risk that their close relatives will also develop MS. We calculated age-adjusted empiric recurrence risks from data on 815 index cases and over 3,000 of their siblings and children. In general, the risk for these relatives to develop MS is 3 to 5%, which is 30 to 50 times the 0.1% rate for the general population.

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