Early Radiation Death in Guinea Pigs

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Abstract
Guinea pigs were exposed to whole body X-radiation at a constant dose rate of 50 r per min. Doses between 1000 and 5000 r caused death in 4-6 days with few neurological changes and typical hem-atological changes. Doses of 7500 to 25, 000 r caused death in less than 24 hours, with marked neurological and hematological changes. These changes were duplicated by irradiation of the head alone. The early death may be attributed to disturbance of the central nervous system.