SPHEROID DEGENERATION OF CONJUNCTIVA AND CORNEA

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Abstract
Patients (26) with spheroid degeneration were followed up after 2 yr. The number of colorless conjunctival droplets increased by an average of 46% (2.alpha. = 0.05) and autofluorescent conjunctival droplets by 223% (2.alpha. < 0.01). Counting within the individual sites disclosed that some droplets disappeared (not less than 30 and 21%, respectively); some droplets recently formed constituted at least 76 and 243%. The number of areas with band-shaped keratopathy rose from 3 to 26 (P < 0.001) out of 104 possibilities (nasally and temporally of right and left eye). Vital staining (fluorescein, rose bengal, tetrazolium and alcian blue) showed that the epithelium above the droplets was intact. The droplet-containing eyes were abnormally dry (break-up time, tear production).

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