Nutritional status of alcoholic patients: it's possible relationship to alcoholic liver damage
Open Access
- 1 September 1983
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 38 (3) , 469-473
- https://doi.org/10.1093/ajcn/38.3.469
Abstract
This study was performed to look for a possible relationship between the nutritional status and the presence of liver damage in alcoholic patients. One hundred chronic alcoholics admitted for treatment to the Alcoholism Ward, without clinical signs of liver failure, were studied. In 84, anthropometric nutritional indexes, liver function tests, and a liver biopsy were performed; in 69 patients a dietary survey was obtained. A dietary imbalance was observed in the total group; 65% of ingested calories were derived from ethanol. The intake of proteins, vitamins, and minerals was below the RDA, NAS/USA, and no differences were found between patients with and without liver damage. Neither were significant differences in daily alcohol calories or total ethanol dose found between both groups of patients. Mean anthropometric values were within 80 to 100% of commonly used standards. However, patients with alcoholic hepatitis and/or cirrhosis had a significantly higher percentage of ideal body weight, compared to alcoholics with normal livers or less severe histological alterations (109.7 ± 20.3 versus 95.6 ± 12.5, SD, p < 0.005). A similar difference was observed in arm muscle areas. These findings show that overweight is associated with liver alterations in the alcoholic and should be investigated as a risk factor to develop liver damage.This publication has 22 references indexed in Scilit:
- Muscle protein breakdown in liver cirrhosis and the role of altered carbohydrate metabolismHepatology, 1981
- Prognostic indicators of hepatic injury following jejunoileal bypass performed for refractory obesity: A prospective studyHepatology, 1981
- Possible relationship between the rate of ethanol metabolism and the severity of hepatic damage in chronic alcoholicsDigestive Diseases and Sciences, 1977
- INSULIN, GLUCAGON, AMINOACID IMBALANCE, AND HEPATIC ENCEPHALOPATHYThe Lancet, 1976
- Alcohol and Dietary Factors in CirrhosisArchives of internal medicine (1960), 1975
- INTESTINAL FUNCTION IN CHRONIC ALCOHOLISM*Annals of the New York Academy of Sciences, 1975
- Fatty Liver, Alcoholic Hepatitis and Cirrhosis Produced by Alcohol in PrimatesNew England Journal of Medicine, 1974
- Effect of ethanol on ketone metabolismJournal of Clinical Investigation, 1970
- Alcohol-Induced Hepatic Injury in Nonalcoholic VolunteersNew England Journal of Medicine, 1968
- The Determination of Ethyl Alcohol in Blood and TissuesPublished by Wiley ,1959