Enhanced Survival of the LINCL Mouse Following CLN2 Gene Transfer Using the rh.10 Rhesus Macaque-derived Adeno-associated Virus Vector
Open Access
- 1 March 2007
- journal article
- Published by Elsevier in Molecular Therapy
- Vol. 15 (3) , 481-491
- https://doi.org/10.1038/sj.mt.6300049
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- CNS-directed AAV2-mediated gene therapy ameliorates functional deficits in a murine model of infantile neuronal ceroid lipofuscinosisMolecular Therapy, 2006
- Efficient Neuronal Gene Transfer with AAV8 Leads to Neurotoxic Levels of Tau or Green Fluorescent ProteinsMolecular Therapy, 2006
- Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brainMolecular Therapy, 2006
- High Levels of Persistent Expression of α1-Antitrypsin Mediated by the Nonhuman Primate Serotype rh.10 Adeno-associated Virus Despite Preexisting Immunity to Common Human Adeno-associated VirusesMolecular Therapy, 2006
- AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCLGene Therapy, 2005
- Adeno-associated virus 2-mediated gene therapy decreases autofluorescent storage material and increases brain mass in a murine model of infantile neuronal ceroid lipofuscinosisNeurobiology of Disease, 2004
- Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous systemGene Therapy, 2003
- Immunological Aspects of Recombinant Adeno-Associated Virus Delivery to the Mammalian BrainJournal of Virology, 2002
- Use of Quantitative TaqMan Real-Time PCR to Track the Time-Dependent Distribution of Gene Transfer Vectors in VivoMolecular Therapy, 2000
- In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vectorGene Therapy, 1998