Differences in the DNA Sequences in the Upstream Attenuator Region of erm (A) in Clinical Isolates of Streptococcus pyogenes and Their Correlation with Macrolide/Lincosamide Resistance
Open Access
- 1 July 2005
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 49 (7) , 3070-3072
- https://doi.org/10.1128/aac.49.7.3070-3072.2005
Abstract
The regulatory regions of 52 erm (A) [formerly erm (TR)] clinical Streptococcus pyogenes isolates were studied. Differences in the upstream regulatory region of erm (A) correlated with macrolide/lincosamide resistance patterns. Nine macrolide/lincosamide/streptogramin B-resistant isolates had changes in the leader sequence of erm (A) including base changes, insertions, or deletions. Isolates were also emm typed.Keywords
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