Experimental Atherosclerosis

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Abstract
The effectiveness of l-cystine, dl-methionine, l-cysteine hydrochloride, l-cysteic acid, cystamine, taurine and reduced glutathione in stimulating growth, production of hemoglobin and reduction in hypercholesteremia of sulfurdeficient monkeys has been studied. These compounds, with the exception of cysteic acid, are shown to be effective. The activities of the compounds are approximately equivalent when compared on a mole sulfur basis except for taurine, which is less effective than the other compounds on a mole sulfur basis, and while it reduces the hypercholesteremia it does not stimulate growth. The relation of these findings to sterol and sulfur metabolism is discussed.