BREAST-CANCER - POTENTIALLY PREDISPOSING AND PROTECTING FACTORS - ROLE OF PREGNANCY, LACTATION, AND ENDOCRINE STATUS
- 1 January 1978
- journal article
- review article
- Vol. 130 (3) , 335-358
Abstract
Risk factors of human breast cancer were correlated with the availability of estradiol and estrone. Mechanisms protecting from breast cancer are thought to be due to the mitotic rest of mammary epithelium (low DNA synthesis), as encountered during pregnancy and lactation, and the actions of estriol and progesterone in opposing carcinogenic estradiol and estrone.This publication has 2 references indexed in Scilit:
- Mechanism of Action of the Sex Steroid HormonesNew England Journal of Medicine, 1976
- Therapeutic castration in the treatment of advanced breast cancerCancer, 1964