Glucaric acid excretion. Analysis of the enzymatic assay and findings in smokers and non-smokers
- 1 January 1980
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Pharmacology
- Vol. 18 (5) , 429-432
- https://doi.org/10.1007/bf00636798
Abstract
Glucaric acid (GA) excretion in urine from cigarette smokers and non-smoking control subjects was determined enzymatically. There was no difference between GA 41.0±3.2 µmol/g creatinine (Cn; mean ± SEM) in smokers and GA 43.1±3.4 µmol/g Cn in the controls. Gas chromatographic analysis of the GA-glucarolactone equilibrium was carried out in an attempt to elucidate the striking discrepancies in previous results.Keywords
This publication has 24 references indexed in Scilit:
- Effect of in vitro changes in urinary pH on the enzymatic measurement and daily variation in excretion of d-glucaric acidJournal of Pharmacy and Pharmacology, 1975
- Change in d-glucaric excertion in relationship to alterations in the rate of antipyrine metabolism in manBiochemical Pharmacology, 1974
- URINARY d‐GLUCARIC ACID EXCRETION AND PLASMA ANTIPYRINE KINETICS DURING ENZYME INDUCTIONBritish Journal of Clinical Pharmacology, 1974
- ETHOSUXIMIDE: LIVER ENZYME INDUCTION AND D‐GLUCARIC ACID EXCRETIONBritish Journal of Clinical Pharmacology, 1974
- A gas-liquid chromatographic method for the determination of d-glucaric acid in urineClinica Chimica Acta; International Journal of Clinical Chemistry, 1974
- Altered Calcium Metabolism in Epileptic Children on AnticonvulsantsBMJ, 1971
- DEVELOPMENTAL EFFECTS ON LIVER d-GLUCURONOLACTONE DEHYDROGENASE LEVELS AND ON d-GLUCARIC ACID EXCRETION IN URINE; HORMONAL EFFECTS ON d-GLUCARIC ACID EXCRETION IN URINEJournal of Endocrinology, 1968
- Differentiation of the barbiturate stimulation of the glucuronic acid pathway from de novo enzyme synthesisBiochemical Pharmacology, 1966
- Biochemical studies on glucuronic acid and glucaric acidAnalytical Biochemistry, 1965
- Evidence for the function of D-glucaric acid as an indicator for drug induced enhanced metabolism through the glucuronic acid pathway in manBiochemical Pharmacology, 1965