No "End of History" for Photolyases
- 5 April 1996
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 272 (5258) , 48-49
- https://doi.org/10.1126/science.272.5258.48
Abstract
In a process called photoreactivation, blue light reverses the chemical damage done to DNA by ultraviolet light. One mediator of this effect is the enzyme CPD photolyase; a second photolyase, (6-4)photolyase, is now reported from Drosophila in a paper in this week9s issue (Todo et al., p. 109). In his Perspective, Sancar describes how this discovery defines a family of light-sensitive enzymes that also includes the blue-light receptors of plants and why it represents a reawakening of the photolyase field.Keywords
This publication has 21 references indexed in Scilit:
- Similarity Among the Drosophila (6-4)Photolyase, a Human Photolyase Homolog, and the DNA Photolyase-Blue-Light Photoreceptor FamilyScience, 1996
- Purification and Partial Characterization of (6‐4) Photoproduct DNA Photolyase from Xenopus laevisPhotochemistry and Photobiology, 1996
- Model studies of the (6-4) photoproduct DNA photolyase: Synthesis and photosensitized splitting of a thymine-5,6-oxetaneJournal of the American Chemical Society, 1995
- Crystal Structure of DNA Photolyase from Escherichia coliScience, 1995
- Photoenzymic repair of UV-damaged DNA: a chemist's perspectiveChemical Society Reviews, 1995
- DNA, sunlight and skin cancerPure and Applied Chemistry, 1995
- A plant gene for photolyase: an enzyme catalyzing the repair of UV‐light‐induced DNA damageThe Plant Journal, 1993
- A new photoreactivating enzyme that specifically repairs ultraviolet light-induced (6-4)photoproductsNature, 1993
- DNA photolyases: Physical properties, action mechanism, and roles in dark repairMutation Research/DNA Repair, 1990
- UV MUTAGENIC PHOTOPRODUCTS IN Escherichia coli AND HUMAN CELLS: A MOLECULAR GENETICS PERSPECTIVE ON HUMAN SKIN CANCER*Photochemistry and Photobiology, 1988