The reaction of aromatic α,β‐unsaturated ketones with 4,5‐diamino‐1,6‐dihydropyrimidin‐6‐ones
- 1 January 1994
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 31 (1) , 61-64
- https://doi.org/10.1002/jhet.5570310111
Abstract
The reaction of 4,5‐diamino‐1,6‐dihydropyrimidin‐6‐ones 1 with one equivalent of the chalcones 2 leads in an acidic medium to the formation of the 2,4‐diaryl‐2,3,6,7‐tetrahydro‐1H‐pyrimido[4,5‐b][1,4]diazepin‐6‐ones 3a‐m. The structure elucidation of the products is based on detailed nmr investigations including selective 13C[1H] decoupling experiments.Keywords
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