MDMA and Parkinsonism
- 3 July 2003
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 349 (1) , 96-97
- https://doi.org/10.1056/nejmc030208
Abstract
Recreational use of 3,4-methylenedioxymethamphetamine (MDMA), or “ecstasy,” has been increasing. MDMA has classically been associated with serotonergic neurotoxicity in humans and in animal models. Recent investigations in nonhuman primates, at doses modeled after those used by humans, revealed severe dopaminergic neurotoxicity with less serotonergic neurotoxicity.1 We report a case of juvenile Parkinson's disease after repeated use of MDMA.Keywords
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