Thyroid Irradiation — One View

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Abstract
Thyroid irradiation is of clinical importance in several circumstances: after administration of 131I for treatment of hyperthyroidism, after external irradiation of the head and neck for benign nonthyroid disease, after exposure of the thyroid to fallout, which contains isotopes of iodine (especially 131I), and after high-dose external irradiation to the neck for nonthyroid malignant disease. In the last situation the major complication is the late development of hypothyroidism and, far less commonly, Graves' ophthalmopathy. In 1949 Quimby and Werner were concerned that 131I therapy for hyperthyroidism might be carcinogenic.1 They used questionnaires to determine the incidence of thyroid tumors in . . .