Vicarious Excretion of Urographic Media

Abstract
Some patients with severe urinary tract disease excrete the urographic contrast material into the gallbladder and bowel by means of both liver detoxification and selective mucosal excretion by the small bowel. The relationship between the degree of renal impairment and this vicarious excretion is uncertain, and the exact mechanism is unknown. Intravenous urography is probably contra-indicated in patients with both renal and hepatic disease.