Effect of Ethanol on Rat Brain Polyphosphoinositides
- 1 March 1984
- journal article
- Published by Wiley in Journal of Neurochemistry
- Vol. 42 (3) , 873-874
- https://doi.org/10.1111/j.1471-4159.1984.tb02762.x
Abstract
Female rats were allowed to consume ethanol during gestation and lactation, and brain polyphosphoinositides of the 21-day-old pups were quantified. Ethanol intake prevented the disappearance of the metabolically labile pools of phosphatidylinositol-4-phosphate and phosphatidylinositol-4,5-bis-phosphate, which are rapidly degraded in the control group. In contrast, preweaning undernutrition left the size of these pools virtually unchanged, indicating a differential effect of the two nutritional regimens.Keywords
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