ON THE "CALORIGENIC ACTION" OF EPINEPHRIN

Publisher Website
Google Scholar
Abstract
The subcutaneous administration of epinephrin to normal dogs causes a marked rise in O consumption and a significant increase in the R. Q. In depancreatized dogs the administration of epinephrin is followed by a definite increase in the O consumption, but no significant change in the R. Q. In eviscerated and hepa-tectomized dogs, epinephrin causes no change in either the O intake (the usual decline continuing) or the R. Q. It is concluded that: the carbohydrate plethora, caused by epinephrin in the normal dog, is not the essential cause of the increased metabolism which follows its administration; insulin bears no direct relationship to the calorigenic action of epinephrin; the calorigenic action of epinephrin does not depend on direct stimulation of tissue cells, the presence of the liver being necessary for such an effect.

This publication has 3 references indexed in Scilit: