Rapid Attainment of Successively Higher Steady-State Plasma Levels Using the Wagner Two-step Infusion Method

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1 December 1978

journal article
research article
Published by Elsevier in Journal of Pharmaceutical Sciences

Vol. 67 (12) , 1651-1656
https://doi.org/10.1002/jps.2600671203

Abstract

No abstract available

Keywords

PLASMA LEVELS—SUCCESSIVELY HIGHER AT STEADY STATE OBTAINED USING TWO-STEP INFUSION METHOD
SIMULATED DATA FOR HYPOTHETICAL DRUG
INFUSION METHODS TWO STEP—USED TO OBTAIN SUCCESSIVELY HIGHER PLASMA LEVELS AT STEADY STATE
PHARMACOKINETICS—SUCCESSIVELY HIGHER PLASMA LEVELS AT STEADY STATE OBTAINED USING TWO-STEP INFUSION METHOD SIMULATED DATA FOR HYPOTHETICAL DRUG

This publication has 6 references indexed in Scilit:

General derivation of the ideal intravenous drug input required to achieve and maintain a constant plasma drug concentration. Theoretical application to lignocaine therapy
European Journal of Clinical Pharmacology, 1976
General theory for rapidly establishing steady state drug concentrations using two consecutive constant rate intravenous infusions
European Journal of Clinical Pharmacology, 1975
A safe method for rapidly achieving plasma concentration plateaus
Clinical Pharmacology & Therapeutics, 1974
A Hypothesis for the Rapid Attainment and Maintenance of Lidocaine Plasma Levels
The Journal of Clinical Pharmacology, 1974
Pharmacokinetics of intravenous theophylline
Clinical Pharmacology & Therapeutics, 1973
Pharmacokinetics of lidocaine in man
Clinical Pharmacology & Therapeutics, 1971