Suppression of PHA-induced lymphocyte blastogenesis by concomitant presence of PPD in the culture
- 1 August 1981
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 37 (8) , 901-903
- https://doi.org/10.1007/bf01985704
Abstract
PHA-induced lymphocyte blastogenic response was remarkably suppressed by the simultaneous presence of PPD in cultures of lymphocytes derived from individuals sensitized to PPD, but not affected by the presence of PPD when the cultures contained lymphocytes from an individual not sensitized to the protein. This double stimulation blastogenesis study with PHA and a specific antigen is feasible as a simple and rapid test to measure cell-mediated immunity to the antigen.Keywords
This publication has 6 references indexed in Scilit:
- PPD-induced blastogenesis is auto-regulated by suppressor cells generated in vitroCellular and Molecular Life Sciences, 1979
- Suppressor Cells Induced by Purified Protein Derivative of Tuberculin (PPD): the Suppression is Mediated by Cells that Proliferate in Response to Stimulation with PPDScandinavian Journal of Immunology, 1979
- Studies on Suppressor Cell Function in Thyroid Diseases*Journal of Clinical Endocrinology & Metabolism, 1979
- Antigen-induced suppression of the in vitro lymphocyte response to different antigens and mitogens.1972