EFFECTS OF DEPTH OF ANESTHESIA ON BEHAVIOR OF PERIPHERAL VASCULAR BED

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Abstract
Light, medium, and deep anesthesia was maintained in 3 groups of 5 dogs by ether, cyclopropane, and Pentothal, respectively. The femoral blood pressure was recorded throughout and the omental circulation observed by direct microscopy. During light anesthesia with all agents the capillary circulation remained practically unimpaired. Moderate anesthesia caused significant changes only with Pentothal where there was depression of the peripheral circulation. Deep anesthesia with ether caused considerable depression of the capillary circulation with marked drop in the systolic pressure. On discontinuing anesthesia there was a lag in the return of vascular tone. Deep cyclopropane anesthesia resulted in capillary depression but to a less degree than with ether; the return to normal was rapid when anesthesia was lightened. Deep anesthesia with Pentothal caused a profound drop in blood pressure, cessation of respiration, and considerable depression of the circulatory mechanism. Recovery was slower than with either of the other agents.

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