METABOLISM OF THE STEROID HORMONES: THE METABOLISM OF TESTOSTERONE IN THE MALE CHIMPANZEE1
- 30 June 1944
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 35 (1) , 22-26
- https://doi.org/10.1210/endo-35-1-22
Abstract
The oral adm. of 1.5 gms. of testosterone propionate to each of 2 adult [male] chimpanzees produced a 13-fold increase in urinary androgenic substances. Androsterone and etio-cholanol-3 ([alpha])-17-one have been identified as urinary metabolites of testosterone in the [male] chimpanzee. This finding is in accord with previous studies on men. Androsterone-17 was also isolated from the urinary extracts but this substance is considered to be formed by dehydration of androsterone during the hydrolysis and extraction of the urine.This publication has 3 references indexed in Scilit:
- EXCRETION OF ESTROGENIC AND ANDROGENIC SUBSTANCES BY FEMALE AND MALE CHIMPANZEES WITH KNOWN MATING BEHAVIOR RECORDS1Endocrinology, 1941
- The isolation of two transformation products of testosterone from urineBiochemical Journal, 1939
- THE DAILY URINARY EXCRETION OF ESTROGENIC AND ANDROGENIC SUBSTANCES BY NORMAL MEN AND WOMEN 1Journal of Clinical Investigation, 1937