THE C- AND O-BENZYLATION OF L-ASCORBIC ACID
- 1 February 1965
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 43 (2) , 450-457
- https://doi.org/10.1139/v65-060
Abstract
Alkylation of sodium L-ascorbate with benzyl chloride yielded a 2-C-benzyl-3-keto-hexulosonic acid lactone and 3-O-benzyl-L-ascorbic acid, the yield of each being dependent on reaction conditions. Other products obtained from the alkylations were 2,3-di-O-benzyl-L-ascorbic acid and a 1-deoxy-1-C-phenyl-2-hexulose. Treatment of 3-O-methyl-5,6-O-isopropylidene-L-ascorbic acid with benzyl chloride and sodium methoxide yielded the 2-O-benzyl derivative.This publication has 10 references indexed in Scilit:
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