NaCl Appetite of Adrenalectomized Rats.

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Abstract
In single-choice experiments, adrenalectomized and normal rats were given choice between distilled water and each of a series of NaCl solutions. The NaCl appetite of adrenalectomized rats was concentration dependent. Adrenalectomized rats preferred NaCl solutions to water until the concentration of the salt solution was .35 [image] or greater. At these higher concentrations the rats preferred water to salt solution. Adrenalectomized rats ingested most NaCl solution (ml/100 g body weight/day) when the concentration was .15 [image]. These rats either lost weight or ceased to gain weight when low (.025 to .050 [image]) and high (.50[image]) NaCl concentrations were given. Body weight of control rats was not influenced by the concentration of NaCl solution offered. Control rats preferred NaCl solution to water at all concentrations below .075 [image]. At concentrations greater than .15 [image], the rats drank more water than NaCl solution. The greatest volume of NaCl solution (ml/100 g body weight/day) was ingested by control rats when a concentration of .05 [image] was given. The maximal difference between intakes of NaCl solution of control and adrenalectomized rats occurred when .15[image] was given. Hence, this concentration would appear to be best fitted to test completeness of adrenalectomy.

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