Muscarinic cholinergic binding sites in an orthopteran central nervous system
- 1 March 1980
- journal article
- research article
- Published by Wiley in Journal of Neurobiology
- Vol. 11 (2) , 215-219
- https://doi.org/10.1002/neu.480110207
Abstract
Homogenates of cricket (Acheta domesticus) central nervous system (CNS) specifically bind the potent muscarinic ligand [3H]-QNB. Binding assay and pharmacologic data indicate that the cricket CNS contains a high density of muscarinic cholinergic binding sites. These sites appear to be a unique class of invertebrate cholinergic receptor with properties distinct from those of previously described nicotinic receptors.Keywords
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