Sequential Autophosphorylation Steps in the Interleukin-1 Receptor-associated Kinase-1 Regulate its Availability as an Adapter in Interleukin-1 Signaling
Open Access
- 1 February 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (7) , 5227-5236
- https://doi.org/10.1074/jbc.m309251200
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Identification of TIFA as an Adapter Protein That Links Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) to Interleukin-1 (IL-1) Receptor-associated Kinase-1 (IRAK-1) in IL-1 Receptor SignalingPublished by Elsevier ,2003
- TICAM-1, an adaptor molecule that participates in Toll-like receptor 3–mediated interferon-β inductionNature Immunology, 2003
- Identification of Threonine 66 as a Functionally Critical Residue of the Interleukin-1 Receptor-associated KinaseJournal of Biological Chemistry, 2002
- Inhibition of Interleukin-1β-induced NF-κB Activation by Calcium/Calmodulin-dependent Protein Kinase Kinase Occurs through Akt Activation Associated with Interleukin-1 Receptor-associated Kinase Phosphorylation and Uncoupling of MyD88Journal of Biological Chemistry, 2002
- Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4Nature, 2002
- Negative Regulation of Toll-like Receptor-mediated Signaling by TollipJournal of Biological Chemistry, 2002
- Defective Interleukin (IL)-18–mediated Natural Killer and T Helper Cell Type 1 Responses in IL-1 Receptor–associated Kinase (IRAK)-deficient MiceThe Journal of Experimental Medicine, 1999
- TRAF6 is a signal transducer for interleukin-1Nature, 1996
- PEST sequences and regulation by proteolysisTrends in Biochemical Sciences, 1996
- Interleukin‐1‐induced activation of a protein kinase co‐precipitating with the type I interleukin‐1 receptor in T cellsEuropean Journal of Immunology, 1994