A NEW APPROACH TO THE STUDY OF GLYCOSIDE HYDROLYSIS

Abstract
Solasodine from Solanum plants is a potential raw material for steroid drug manufacture. Acid hydrolysis of the naturally occurring glycosides of solasodine is a major step in production of the aglycone. In this study, high pressure liquid chromatography is being used to follow the sequence of sugar cleavage reactions during hydrolysis. A kinetic model has been developed to describe the hydrolysis reactions.