DISSEMINATED HERPES SIMPLEX VIRUS INFECTION IN ATAXIA‐TELANGIECTASIA
- 1 September 1978
- journal article
- research article
- Published by Wiley in Acta Paediatrica
- Vol. 67 (5) , 667-670
- https://doi.org/10.1111/j.1651-2227.1978.tb17821.x
Abstract
The clinical and pathological features are described in a child with ataxia-telangiectasia, complicated by fatal disseminated herpes simplex virus infection. Herpes simplex virus was isolated from the patient''s blood, and the histopathological findings in the skin, liver and adrenals were consistent with herpes simplex virus infection. The patient had a combined immune deficiency state, as a part of the ataxia-telangiectasia syndrome. She had impaired cellular immune response to herpes simplex virus and developed no antibodies against the virus. This is the 1st fatal case of disseminated herpes simplex virus infection in ataxia-telangiectasia.Keywords
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