Population genetics—making sense out of sequence
- 1 January 1999
- journal article
- review article
- Published by Springer Nature in Nature Genetics
- Vol. 21 (S1) , 56-60
- https://doi.org/10.1038/4482
Abstract
The complete human genome nucleotide sequence and technologies for assessing sequence variation on a genome–scale will prompt comprehensive studies of comparative genomic diversity in human populations across the globe. These studies, besides rejuvenating population genetics and our interest in how genetic variation is created and maintained, will provide the intellectual basis for understanding the genetic basis for complex diseases and traits.Keywords
This publication has 46 references indexed in Scilit:
- Molecular interactions on microarraysNature Genetics, 1999
- Shotgun Sequencing of the Human GenomeScience, 1998
- HumanGFRA1: Cloning, Mapping, Genomic Structure, and Evaluation as a Candidate Gene for Hirschsprung Disease SusceptibilityGenomics, 1998
- Duplication of a gene-rich cluster between 16p11.1 and Xq28: a novel pericentromeric-directed mechanism for paralogous genome evolutionHuman Molecular Genetics, 1996
- Genetic Dissection of Complex TraitsScience, 1994
- Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selectionNature, 1988
- DNA sequence variants in the Gγ-, Aγ-, δ- and β-globin genes of manCell, 1979
- Evolution and the Genetics of Populations, Volume 4: Variability within and among Natural Populations.Published by JSTOR ,1979
- Gene Differences between Caucasian, Negro, and Japanese PopulationsScience, 1972
- Evolution and the Genetics of Populations. Volume 2: The Theory of Gene Frequencies.Published by JSTOR ,1971